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Estructura de un receptor de adenosina A2A humano unido al agonista

Fei Xu1, Huixian Wu, Vsevolod Katritch

  • 1Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 12, 2011
PubMed
Resumen

La estructura cristalina del receptor de adenosina A2A unido al agonista UK-432097 revela cambios conformacionales clave. Este agonista estabiliza el receptor en un estado activo específico, crucial para la señalización del receptor acoplado a la proteína G.

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