Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Motivation levels and white matter microstructure in children living with HIV.

Scientific reports·2024
Same author

A comparison of vitamin D and cathelicidin (LL-37) levels between patients with active TB and their healthy contacts in a high HIV prevalence setting: a prospective descriptive study.

Transactions of the Royal Society of Tropical Medicine and Hygiene·2021
Same author

Determine TB-LAM point-of-care tuberculosis assay predicts poor outcomes in outpatients during their first year of antiretroviral therapy in South Africa.

BMC infectious diseases·2020
Same author

Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults.

The New England journal of medicine·2020
Same author

Tuberculosis in Hospitalized Patients With Human Immunodeficiency Virus: Clinical Characteristics, Mortality, and Implications From the Rapid Urine-based Screening for Tuberculosis to Reduce AIDS Related Mortality in Hospitalized Patients in Africa.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2019
Same author

Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study.

PLoS medicine·2019
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Jun 3, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

La tuberculosis es la tuberculosis.

Stephen D Lawn1, Alimuddin I Zumla

  • 1The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

Lancet (London, England)
|March 23, 2011
PubMed
Resumen

La tuberculosis sigue siendo una crisis de salud mundial, causando millones de muertes al año. La inversión urgente y el compromiso político son vitales para desarrollar nuevos diagnósticos, medicamentos y vacunas para combatir esta enfermedad infecciosa persistente.

Videos de Experimentos Relacionados

Last Updated: Jun 3, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Área de la Ciencia:

  • Salud Pública La salud pública.
  • Enfermedades infecciosas Enfermedades infecciosas.
  • Epidemiología La epidemiología.

Sus antecedentes:

  • La tuberculosis (TB) causa más de 1,7 millones de muertes y 9 millones de nuevos casos al año, afectando desproporcionadamente a los países de bajos y medianos ingresos.
  • El VIH aumenta significativamente la susceptibilidad a la tuberculosis, particularmente en el África subsahariana, donde se producen cuatro de cada cinco casos de tuberculosis asociados al VIH.
  • Los diagnósticos y tratamientos actuales para la tuberculosis (microscopía de esputo) son inadecuados, y se enfrentan a desafíos como la resistencia a los medicamentos y los regímenes prolongados.

Objetivo del estudio:

  • Para presentar las perspectivas actuales sobre la epidemia mundial de tuberculosis.
  • Revisar el patógeno, la respuesta del huésped y los métodos de control emergentes para la tuberculosis.
  • Para resaltar los desafíos en curso en el control de la tuberculosis en el siglo XXI.

Principales métodos:

  • Revisión de la literatura científica actual y la investigación sobre la tuberculosis.
  • Análisis de los datos epidemiológicos sobre la incidencia de la tuberculosis, la mortalidad y la resistencia a los medicamentos.
  • Síntesis de información sobre diagnósticos, biomarcadores, medicamentos y vacunas para la tuberculosis.

Principales resultados:

  • Los avances significativos en la ciencia básica y la investigación traslacional han dado lugar a desarrollos prometedores en el diagnóstico de la TB, los biomarcadores, los medicamentos y las vacunas.
  • El aumento de las tasas de tuberculosis resistente a los medicamentos amenaza los esfuerzos globales de control.
  • La comprensión fundamental de la patogénesis de la tuberculosis sigue siendo inadecuada.

Conclusiones:

  • A pesar de los avances, la tuberculosis sigue siendo un gran desafío mundial de salud pública que requiere una mayor inversión y compromiso político.
  • Nuevos diagnósticos, medicamentos efectivos y vacunas son cruciales para el control de la epidemia de tuberculosis.
  • Abordar los desafíos multifacéticos del control de la tuberculosis requiere un esfuerzo global integral y sostenido.