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La proteína quinasa activada por AMP regula la polarización neuronal al interferir con la localización de la PI

Stephen Amato1, Xiuxin Liu, Bin Zheng

  • 1Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA.

Science (New York, N.Y.)
|March 26, 2011
PubMed
Resumen

La activación de la vía de la adenosina 5'-monofosfato (AMP) activada por la proteína quinasa (AMPK) que detecta la energía suprime la polarización neuronal. Esto ocurre al interrumpir el transporte de proteínas motoras de fosfatidilinositol 3-cinasa (PI3K) a la punta del axón, inhibiendo el crecimiento.

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