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La corriente tardía de sodio contribuye al efecto inverso dependiente de la velocidad de la inhibición de IKr en la

Lin Wu1, Jihua Ma, Hong Li

  • 1Department of Biology, Gilead Sciences, 1651 Page Mill Road, Palo Alto, CA 94304, USA. lin971@yahoo.com

Circulation
|April 13, 2011
PubMed
Resumen

La inhibición de la corriente de sodio tardía (I(Na tardía)) mitiga la dependencia proarrítmica de la tasa de reversión de los bloqueadores de I(Kr). Este hallazgo sugiere que el I ((Na) tardío contribuye a las arritmias ventriculares relacionadas con la bradicardia.

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