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Sustitución del serotipo en la enfermedad después de la vacunación neumocócica

Daniel M Weinberger1, Richard Malley, Marc Lipsitch

  • 1Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA. weinbergerdm@mail.nih.gov

Lancet (London, England)
|April 16, 2011
PubMed
Resumen

La vacuna conjugada neumocócica heptavalente (PCV7) redujo la enfermedad pero aumentó los serotipos no vacunados (NVTs). El reemplazo del serotipo en la enfermedad es menor que en el transporte debido a la invasividad de la TNV y los sesgos de vigilancia.

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