Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...
Spectroscopy of Carboxylic Acid Derivatives01:26

Spectroscopy of Carboxylic Acid Derivatives

Infrared spectroscopy is primarily used to determine the types of bonds and functional groups. In carboxylic acid derivatives, a typical carbonyl bond absorption is observed around 1650–1850 cm−1. For esters, the absorption is recorded at around 1740 cm−1, while acid halides show the absorption at about 1800 cm−1. Another acid derivative, the acid anhydrides, exhibit two carbonyl absorption around 1760 cm−1 and 1820 cm−1, arising from the symmetrical and unsymmetrical carbonyl vibration.
In the...
Applications of IR Spectroscopy: Overview01:11

Applications of IR Spectroscopy: Overview

The non-destructive nature and ability to provide valuable chemical information make IR spectroscopy a versatile technique with broad applications in various scientific and industrial fields. IR spectroscopy is commonly used to identify and characterize organic and inorganic compounds. It provides information about the functional groups present in a molecule and the bonding between atoms. This helps in the structural elucidation of compounds during organic synthesis, pharmaceutical research,...
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration01:16

IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration

A covalently bonded heteronuclear diatomic molecule can be modeled as two vibrating masses connected by a spring. The vibrational frequency of the bond can be expressed using an equation derived from Hooke's law, which describes how the force applied to stretch or compress a spring is proportional to the displacement of the spring. In this case, the atoms behave like masses, and the bond acts like a spring.
According to Hooke's law, the vibrational frequency is directly proportional to the...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Robust single-scan ultraselective NMR.

Chemical communications (Cambridge, England)·2026
Same author

General Nuclear Magnetic Resonance Analysis Toolbox for Stats: A Comprehensive Module for Nuclear Magnetic Resonance-Based Chemometrics and Metabolomics.

Analytical chemistry·2026
Same author

Practical Guide and Best Practices for Diffusion NMR Processing With GNAT.

Magnetic resonance in chemistry : MRC·2026
Same author

Real-Time NMR Quantification of Paramagnetic Species during Chemical Reactions.

Analytical chemistry·2026
Same author

Full-Signal Ultrahigh-Resolution NMR by Parameter Estimation.

Analytical chemistry·2025
Same author

<sup>1</sup>H NMR Pure Shift Metabolomic Analysis of Black Tea.

Analytical chemistry·2025

Video Experimental Relacionado

Updated: Jun 2, 2026

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
06:55

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Published on: September 26, 2016

Espectroscopia ordenada por difusión ordenada por covarianza local: una poderosa herramienta para el análisis de

Adam A Colbourne1, Gareth A Morris, Mathias Nilsson

  • 1School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK.

Journal of the American Chemical Society
|May 3, 2011
PubMed
Resumen
Este resumen es generado por máquina.

La Orden de Covariancia Local DOSY (LOCODOSY) mejora el análisis de mezclas de Resonancia Magnética Nuclear (RMN). Este nuevo método híbrido resuelve efectivamente mezclas complejas mediante el análisis de ventanas espectrales, mejorando significativamente la separación de componentes más allá de los métodos tradicionales.

Más Videos Relacionados

O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
06:50

O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression

Published on: November 8, 2019

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics
13:16

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics

Published on: July 31, 2021

Videos de Experimentos Relacionados

Last Updated: Jun 2, 2026

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
06:55

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

Published on: September 26, 2016

O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
06:50

O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression

Published on: November 8, 2019

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics
13:16

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics

Published on: July 31, 2021

Área de la Ciencia:

  • Química Analítica La Química Analítica es la
  • Química orgánica es la química orgánica.
  • Química supramolecular de las moléculas.

Sus antecedentes:

  • La espectroscopia ordenada por difusión (DOSY) es crucial para el análisis de mezclas de RMN.
  • DOSY ayuda a desentrañar los espectros y determinar los coeficientes de difusión para obtener información sobre el tamaño y la interacción.
  • El DOSY de alta resolución lucha con espectros superpuestos en mezclas complejas.

Objetivo del estudio:

  • Introducir un nuevo método híbrido, LOCODOSY, para el procesamiento de datos de difusión de RMN.
  • Para superar las limitaciones del DOSY tradicional en el análisis de mezclas altamente complejas.
  • Para mejorar la resolución de los espectros de componentes individuales en conjuntos de datos de RMN superpuestos.

Principales métodos:

  • Desarrollo de un método híbrido: Orden de covarianza local DOSY (LOCODOSY).
  • Los datos espectrales se dividen en ventanas para el análisis individual.
  • Los algoritmos multivariados (por ejemplo, SCORE, DECRA) se aplican dentro de cada ventana.

Principales resultados:

  • LOCODOSY aumenta dramáticamente el número de componentes químicos disolubles.
  • Se logra una resolución completa de los espectros de los componentes para mezclas complejas anteriormente inmanejables.
  • Demuestra un rendimiento superior en comparación con el DOSY de alta resolución tradicional para muestras complejas.

Conclusiones:

  • LOCODOSY es una herramienta potente y flexible para el procesamiento de datos de difusión de RMN.
  • Este método avanza significativamente en el análisis de mezclas químicas complejas.
  • LOCODOSY amplía la aplicabilidad de DOSY en varias disciplinas químicas.