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El receptor de estrógeno transreprime la inflamación cerebral
1Laboratory of Endocrinology and Genomics, CHUQ Research Center and Department of Molecular Medicine, Faculty of Medicine, Laval University, 2705 Laurier Boulevard, Québec, G1V 4G2, Canada.
Cell
|May 14, 2011
Resumen
El receptor beta del estrógeno (ERβ) juega un papel clave en la esclerosis múltiple. Esta vía suprime la inflamación y ralentiza la progresión de la enfermedad en un modelo de ratón, ofreciendo nuevos objetivos terapéuticos.
Área de la Ciencia:
- Neuroinmunología La neuroinmunología.
- Endocrinología Endocrinología.
Sus antecedentes:
- Los receptores de estrógenos (RE) están vinculados a la etiología de la esclerosis múltiple (EM).
- Los mecanismos moleculares precisos que conectan las ER con la patología de la EM siguen sin estar claros.
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