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Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
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La estructura cristalina del transportador de maltosa en un estado intermedio de pretranslocación

Michael L Oldham1, Jue Chen

  • 1Department of Biological Sciences, Purdue University, Howard Hughes Medical Institute, West Lafayette, IN 47907, USA.

Science (New York, N.Y.)
|May 14, 2011
PubMed
Resumen

Los sustratos inician ciclos de transporte en los transportadores de adenosina trifosfato (ATP) y cinta de unión (ABC) al inducir cambios conformacionales. La unión de ATP entonces impulsa la progresión hacia el estado orientado hacia el exterior, revelando mecanismos de comunicación alostéricos.

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