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Updated: Jun 7, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
11:07

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding

Published on: September 21, 2011

Interferencia transcripcional entre c-Jun y el receptor glucocorticoide: inhibición mutua de la unión al ADN debido a

H F Yang-Yen1, J C Chambard, Y L Sun

  • 1Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093.

Cell
|September 21, 1990
PubMed
Resumen

Los receptores de glucocorticoides (GCR) inhiben la actividad del gen de la collagenasa mediante la represión de AP-1. Este estudio revela interacciones directas entre las proteínas GCR y Jun/Fos, descubriendo un nuevo mecanismo de represión transcripcional.

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