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Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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Published on: October 10, 2020

Una glutatión S-transferasa dedicada media la formación de enlaces carbono-azufre en la biosíntesis de la gliotoxina

Daniel H Scharf1, Nicole Remme, Andreas Habel

  • 1Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstr. 11a, 07745 Jena, Germany.

Journal of the American Chemical Society
|July 14, 2011
PubMed
Resumen

Este estudio revela cómo GliG, una glutatión S-transferasa (GST), crea enlaces de azufre en la gliotoxina, una toxina clave de Aspergillus fumigatus. Este hallazgo es crucial para comprender la aspergilosis invasiva.

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