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Updated: May 30, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Síntesis total de (-) -N-metilwelwitindolinona C y el isotiocianato

Alexander D Huters1, Kyle W Quasdorf, Evan D Styduhar

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|August 9, 2011
PubMed
Resumen

Los investigadores lograron la primera síntesis total de (-) -N-metilwelwitindolinona C isotiocianato, un producto natural complejo. Los pasos clave incluyeron la ciclización de indolina y la inserción de nitreno para el montaje del andamio y la funcionalización del carbono de la cabeza de puente.

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