Search research articles

ACERCA DE JoVE

Visión General Liderazgo Blog Centro de Ayuda JoVE

AUTORES

Proceso de Publicación Consejo Editorial Alcance y Políticas Revisión por Pares Preguntas Frecuentes Enviar

BIBLIOTECARIOS

Testimonios Suscripciones Acceso Recursos Consejo Asesor de Bibliotecas Preguntas Frecuentes

INVESTIGACIÓN

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archivo

EDUCACIÓN

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Centro de Recursos para Profesores Sitio de Profesores

Términos y Condiciones de Uso

Política de Privacidad

Videos de Conceptos Relacionados

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...

Chronic Kidney Disease III: Interprofessional Care

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...

Nephrons

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...

Chronic Kidney Disease IV: Nursing Management

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...

Diabetic Nephropathy

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por

Same author

Measured and Estimated Glomerular Filtration Rates and Risk of Adverse Health Outcomes.

JAMA·2026

Same author

Glomerular Filtration Markers: Current and Emerging Insights.

Clinical journal of the American Society of Nephrology : CJASN·2026

Same author

Medications Influencing Serum Cystatin C Independent of Measured GFR.

Journal of the American Society of Nephrology : JASN·2026

Same author

Determining baseline serum creatinine in harmonized criteria for kidney disease: unfinished business.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026

Same author

Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

Kidney international·2026

Same author

Metabolomic Changes After Bariatric Surgery Adjusted for Glomerular Filtration Rate Suggest Mechanisms of Kidney Protection.

Obesity (Silver Spring, Md.)·2025

Same journal

Assisted dying and the silencing of medicine's next generation.

Lancet (London, England)·2026

Same journal

Linguistic pragmatism: a woman with progressive abdominal pain in Thailand.

Lancet (London, England)·2026

Same journal

Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

Lancet (London, England)·2026

Same journal

[<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

Lancet (London, England)·2026

Same journal

Research priorities for characterising Bundibugyo virus.

Lancet (London, England)·2026

Same journal

Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

Lancet (London, England)·2026

Ver todos los artículos relacionados

Search research articles

Video Experimental Relacionado

Updated: May 30, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Enfermedad renal crónica enfermedad renal crónica.

Andrew S Levey¹, Josef Coresh

¹William B Schwartz Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA. alevey@tuftsmedicalcenter.org

Lancet (London, England)

|August 16, 2011

Resumen

Este resumen es generado por máquina.

La enfermedad renal crónica (ERC) es un problema de salud mundial que afecta la función renal. La detección temprana a través de pruebas de rutina y el manejo basado en la tasa de filtración glomerular (GFR) y la albuminuria pueden retrasar la progresión y mejorar los resultados.

Más Videos Relacionados

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

Published on: February 10, 2026

Videos de Experimentos Relacionados

Last Updated: May 30, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

Published on: February 10, 2026

Área de la Ciencia:

Nefrología Nefrología.
Salud Pública La salud pública.
Medicina interna es la medicina interna de las enfermedades.

Sus antecedentes:

La enfermedad renal crónica (ERC) abarca diversos trastornos que afectan la estructura y la función renal.
Las directrices de 2002 marcaron un cambio significativo, al reconocer la ERC como una preocupación mundial de salud pública que requiere la intervención temprana de internistas generales.
El manejo y la clasificación de la ERC se escalan de acuerdo con la gravedad de la enfermedad, utilizando la tasa de filtración glomerular (GFR) y la albuminuria, junto con el diagnóstico clínico.

Objetivo del estudio:

Para discutir la carga global de la enfermedad renal crónica.
Para delinear recomendaciones para la evaluación y gestión de CKD.
Identificar futuros desafíos y áreas de incertidumbre en el cuidado de la ERC.

Principales métodos:

Revisión de las directrices de práctica clínica para la ERC.
Análisis de datos de ensayos clínicos relacionados con la ERC.
Discusión de los criterios de diagnóstico, incluidos los niveles de GFR y albuminuria.

Principales resultados:

CKD es detectable a través de pruebas de laboratorio de rutina.
Las intervenciones tempranas pueden prevenir el desarrollo de la enfermedad y retrasar su progresión.
El manejo efectivo reduce las complicaciones, el riesgo de enfermedades cardiovasculares y mejora la supervivencia y la calidad de vida.

Conclusiones:

La ERC requiere un enfoque de salud pública con estrategias de manejo temprano.
La estadificación de la ERC utilizando el GFR y la albuminuria es crucial para un tratamiento eficaz.
La investigación continua y el cumplimiento de las directrices clínicas son vitales para abordar los desafíos de la ERC.