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La enfermedad cardíaca puede ser un factor de riesgo para la embolia pulmonar sin trombosis venosa profunda
Henrik T Sørensen1, Erzsebet Horvath-Puho, Timothy L Lash
1Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Allé 43-45, DK-8200 Aarhus N, Denmark. hts@dce.au.dk
Circulation
|September 9, 2011
Resumen
Las enfermedades del corazón elevan significativamente el riesgo de embolia pulmonar (EP) sin trombosis venosa profunda (TVP) concurrente. Este estudio confirma una fuerte asociación entre los eventos cardíacos anteriores y la EP aislada, destacando una importante consideración clínica.
Área de la Ciencia:
- Cardiología Cardiología.
- La medicina vascular es una medicina vascular.
- Epidemiología La epidemiología.
Sus antecedentes:
- Las enfermedades del corazón son factores de riesgo conocidos para la embolia arterial.
- La asociación entre la enfermedad cardíaca y la embolia pulmonar (EP) específicamente sin trombosis venosa periférica (TVP) requiere más aclaraciones.
Objetivo del estudio:
- Investigar la relación entre la enfermedad cardíaca anterior y el riesgo de embolia pulmonar, particularmente PE aislado.
- Para cuantificar el riesgo de EP y trombosis venosa profunda (TVP) en pacientes con antecedentes de enfermedad cardíaca.
Principales métodos:
- En Dinamarca se llevó a cabo un estudio de caso-control a nivel nacional basado en la población.
- Los datos de 1980-2007 incluyeron pacientes diagnosticados con EP y / o TVP, con controles de población.
- Las proporciones de probabilidades se calcularon para evaluar los riesgos relativos de enfermedades cardíacas anteriores con diferentes resultados de tromboembolismo venoso.
Principales resultados:
- El infarto de miocardio y la insuficiencia cardíaca en los 3 meses anteriores aumentaron significativamente el riesgo de EP aislada (OR 43.5 y 32.4, respectivamente).
- Los riesgos de PE combinada y TVP, y TVP sola, fueron más bajos en comparación con PE aislada.
- La enfermedad valvular del lado derecho mostró una proporción de probabilidades sustancialmente mayor para la EP (74,6) que la izquierda (13,5).
Conclusiones:
- Las enfermedades cardíacas aumentan sustancialmente el riesgo a corto plazo de embolia pulmonar.
- El riesgo es particularmente elevado para la EP que ocurre sin un diagnóstico de trombosis venosa periférica.
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