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Una α-arilación enantioselectiva e intermolecular de los enolados de éster para formar estereocentros terciarios

Zhiyan Huang1, Zheng Liu, Jianrong Steve Zhou

  • 1Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.

Journal of the American Chemical Society
|September 14, 2011
PubMed
Resumen

Los investigadores desarrollaron un nuevo catalizador de paladio para la alfa-arilación asimétrica, lo que permite la creación eficiente de centros terciarios. Este método logra una alta enantioselectividad, demostrada por la síntesis de (S) -naproxeno con una excelente pureza.

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