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Beber el elixir de la juventud
William Mair1, Kristan K Steffen, Andrew Dillin
1The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. wmair@hsph.harvard.edu
Cell
|September 20, 2011
Resumen
La proteína quinasa activada por AMP (AMPK) es un sensor de combustible celular relacionado con el envejecimiento. La investigación muestra que la desacetilación de Sip2 en la levadura regula la vida útil, actuando como un reloj de envejecimiento modificable.
Área de la Ciencia:
- La bioquímica es la bioquímica.
- Biología celular Biología celular.
- Investigación sobre el envejecimiento Investigación sobre el envejecimiento
Sus antecedentes:
- La proteína quinasa activada por AMP (AMPK) es un sensor de energía celular crucial involucrado en la regulación metabólica.
- Las vías de señalización de AMPK son cada vez más reconocidas por su papel en el proceso de envejecimiento en varios organismos.
- Comprender los mecanismos moleculares subyacentes al envejecimiento es vital para desarrollar intervenciones para promover la longevidad.
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