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Updated: May 28, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

Etiquetado específico del sitio del ADN y el ARN utilizando una clase de pares de bases no naturales eficientemente

Young Jun Seo1, Denis A Malyshev, Thomas Lavergne

  • 1Department of Chemistry and Center for Protein and Nucleic Acid Research, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|October 11, 2011
PubMed
Resumen

Los investigadores desarrollaron nuevos pares de bases antinaturales para el etiquetado de ADN y ARN específico del sitio. Estos nucleótidos modificados permiten una síntesis enzimática eficiente y la funcionalización posterior a la síntesis para diversas aplicaciones.

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