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Updated: May 28, 2026

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Detección por RMN de estructuras en el ARN 5'-líder del VIH-1 que regulan el empaque del genoma

Kun Lu1, Xiao Heng, Lianko Garyu

  • 1Howard Hughes Medical Institute (HHMI) and Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, MD 21250, USA.

Science (New York, N.Y.)
|October 15, 2011
PubMed
Resumen

El líder del ARN del VIH-1 utiliza un interruptor estructural para controlar la replicación viral. Este interruptor regula la dimerización del genoma, la unión a las proteínas de los nucleocápsidos y el envasado, revelando un mecanismo clave en el ensamblaje viral.

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