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Desarrollo basado en clúster de boro de potentes ligandos no secosteroidales del receptor de vitamina D: observación

Shinya Fujii1, Hiroyuki Masuno, Yoshiyuki Taoda

  • 1Graduate School of Biomedical Science, Tokyo Medical and Dental University, 2-3-10, Kanda-Surugadai, Tokyo 101-0062, Japan.

Journal of the American Chemical Society
|November 10, 2011
PubMed
Resumen

Los investigadores diseñaron un nuevo agonista del receptor de vitamina D (VDR) utilizando un núcleo de carborano hidrofóbico estable. Este ligando VDR basado en carborano muestra una actividad moderada, lo que demuestra el carborano.

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