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Monitoring Protein-RNA Interaction Dynamics In Vivo at High Temporal Resolution Using χCRAC
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Los tRNA marcados con CCACCA están dirigidos a la degradación

Jeremy E Wilusz1, Joseph M Whipple, Eric M Phizicky

  • 1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. wilusz@mit.edu

Science (New York, N.Y.)
|November 15, 2011
PubMed
Resumen

La enzima de adición de CCA marca los ARN de transferencia inestables (ARNt) para la degradación mediante la adición de CCACCA en lugar de CCA. Este proceso, observado en todos los reinos de la vida, ayuda a controlar los niveles de tRNA y evitar errores de traducción.

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