Video Experimental Relacionado

Updated: May 26, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

La restricción de la actividad enzimática en la xantina oxidorreductaasa por la conformación proteica

Hiroshi Ishikita1, Bryan T Eger, Ken Okamoto

  • 1Career-Path Promotion Unit for Young Life Scientists, Kyoto University, 202 Building E, Graduate School of Medicine, Kyoto 606-8501, Japan. hiro@cp.kyoto-u.ac.jp

Journal of the American Chemical Society
|December 8, 2011
PubMed
Resumen

Las enzimas de la xantina oxidorreductaza (XDH/XO) difieren en la transferencia de electrones a pesar de tener estructuras idénticas. Un cambio conformacional del bucle cerca del sitio de la flavina explica la diferencia de potencial redox entre XDH y XO.

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