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Embryonic Stem Cells00:57

Embryonic Stem Cells

5.9K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
5.9K
Embryonic Stem Cells00:58

Embryonic Stem Cells

33.4K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
33.4K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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Video Experimental Relacionado

Updated: Mar 29, 2026

Trans-inner Cell Mass Injection of Embryonic Stem Cells Leads to Higher Chimerism Rates
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Trans-inner Cell Mass Injection of Embryonic Stem Cells Leads to Higher Chimerism Rates

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Primates quiméricos: las células madre embrionarias no necesitan aplicarse.

Alan Trounson1, Uta Grieshammer

  • 1California Institute for Regenerative Medicine, 210 King Street, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov

Cell
|January 10, 2012
PubMed
Resumen
Este resumen es generado por máquina.

Los investigadores crearon las primeras quimeras de mono rhesus. Este avance en la generación de quimeras de primates no humanos se logró agregando embriones de cuatro células, no inyectando células madre embrionarias.

Área de la Ciencia:

  • Biología del desarrollo Biología del desarrollo.
  • La investigación en primates es un trabajo de investigación.

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  • Biología de las células madre Biología de las células madre

    • Sus antecedentes:

    • La generación de quimeras viables es crucial para estudiar el desarrollo temprano y el modelado de enfermedades.
    • Los intentos anteriores de crear quimeras de primates no humanos utilizando células madre embrionarias no han tenido éxito.
    • Las quimeras de ratones se generan rutinariamente inyectando células madre embrionarias en blastocistos.