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Primates quiméricos: las células madre embrionarias no necesitan aplicarse
Alan Trounson1, Uta Grieshammer
1California Institute for Regenerative Medicine, 210 King Street, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov
Cell
|January 10, 2012
Resumen
Los investigadores crearon las primeras quimeras de mono rhesus. Este avance en la generación de quimeras de primates no humanos se logró agregando embriones de cuatro células, no inyectando células madre embrionarias.
Área de la Ciencia:
- Biología del desarrollo Biología del desarrollo.
- La investigación en primates es un trabajo de investigación.
- Biología de las células madre Biología de las células madre
Sus antecedentes:
- La generación de quimeras viables es crucial para estudiar el desarrollo temprano y el modelado de enfermedades.
- Los intentos anteriores de crear quimeras de primates no humanos utilizando células madre embrionarias no han tenido éxito.
- Las quimeras de ratones se generan rutinariamente inyectando células madre embrionarias en blastocistos.
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