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Videos de Conceptos Relacionados

Centrioles and Centrosomes01:13

Centrioles and Centrosomes

Most animal cells comprise a pair of centrioles together called a centrosome. The cell duplicates its centrosome and contains two centrosomes side-by-side, which begin to move apart during the prophase. As the centrosomes migrate to two different sides of the cell, microtubules start extending from each centrosome toward the other end. The mitotic spindle is composed of the centrosomes and their emerging microtubules.
Near the end of the prophase, also called late prophase or "prometaphase,"...
Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
Histone Variants at the Centromere02:30

Histone Variants at the Centromere

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3 variants are also...
The Mitotic Spindle02:27

The Mitotic Spindle

The mitotic spindle—or spindle apparatus—is a eukaryotic, cytoskeletal structure made up of long protein fibers called microtubules. Formed during cell division, the spindle separates sister chromatids and moves them to opposite ends of a parental cell, where the now individual chromosomes are distributed to two daughter cell nuclei.
The bipolar configuration of the mitotic spindle facilitates chromosomal segregation, preparing the cell for division. One mechanism that ensures bipolar mitotic...
The Mitotic Spindle02:27

The Mitotic Spindle

The mitotic spindle—or spindle apparatus—is a eukaryotic, cytoskeletal structure made up of long protein fibers called microtubules. Formed during cell division, the spindle separates sister chromatids and moves them to opposite ends of a parental cell, where the now individual chromosomes are distributed to two daughter cell nuclei.
The bipolar configuration of the mitotic spindle facilitates chromosomal segregation, preparing the cell for division. One mechanism that ensures bipolar mitotic...

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Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis.

The EMBO journal·2022
Same author

Acto-myosin network geometry defines centrosome position.

Current biology : CB·2021
Same author

Centrosome organization and functions.

Current opinion in structural biology·2020
Same author

A helical inner scaffold provides a structural basis for centriole cohesion.

Science advances·2020
Same author

A moment at the cell centre.

Biology of the cell·2019
Same author

[Cell polarity and the innovation of the primary cilium/centrosome organ in Metazoa].

Medecine sciences : M/S·2019

Video Experimental Relacionado

Updated: May 25, 2026

Imaging Centrosomes in Fly Testes
09:41

Imaging Centrosomes in Fly Testes

Published on: September 20, 2013

El centrosoma en las células y los organismos.

Michel Bornens1

  • 1UMR144 du Centre Nationale de la Recherche Scientifique, Institut Curie, 26 rue d'Ulm, Paris Cedex 05, France. mbornens@curie.fr

Science (New York, N.Y.)
|January 28, 2012
PubMed
Resumen

El centrosoma, crucial para la división celular y la polaridad, no está universalmente presente en todos los organismos. Su papel en el posicionamiento del núcleo y la definición de la polaridad del embrión pone de relieve su importancia evolutiva.

Área de la Ciencia:

  • Biología celular Biología celular.
  • Biología evolutiva Biología evolutiva.
  • Genética La genética.

Sus antecedentes:

  • El centrosoma es el orgánulo primario de nucleación de microtúbulos en las células animales.
  • Es esencial para la orientación del huso mitótico y el mantenimiento de la estabilidad del genoma.
  • Los centrosomas están ausentes en algunos organismos multicelulares y en tipos específicos de células.

Objetivo del estudio:

  • Para discutir el papel del centrosoma en el establecimiento de la polaridad celular.
  • Explorar cómo la función del centrosoma influye en el posicionamiento nuclear.
  • Examinar el impacto potencial de la innovación del centrosoma en la evolución de los metazoos.

Principales métodos:

  • Revisión de la literatura existente sobre la función del centrosoma.

Más Videos Relacionados

Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes
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Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes

Published on: December 20, 2014

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
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Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles

Published on: September 21, 2018

Videos de Experimentos Relacionados

Last Updated: May 25, 2026

Imaging Centrosomes in Fly Testes
09:41

Imaging Centrosomes in Fly Testes

Published on: September 20, 2013

Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes
09:39

Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes

Published on: December 20, 2014

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
10:38

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles

Published on: September 21, 2018

  • Análisis del papel del centrosoma en la división celular y la polaridad.
  • Análisis evolutivo comparativo de la presencia y función del centrosoma.

    • Principales resultados:

    • La reproducción del centrosoma transmite la polaridad a las células hijas.
    • El centrosoma donado por el esperma típicamente establece la polaridad del embrión.
    • Los centrosomas son la clave para posicionar el núcleo centralmente dentro de la célula.

    Conclusiones:

    • El centrosoma es vital para la polaridad celular y la organización nuclear.
    • La innovación del centrosoma puede haber sido un factor crítico en la evolución de los metazoos.