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Updated: May 25, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
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Probar enlaces de hidrógeno de Hoogsteen transitorios en el ADN dúplex canónico utilizando dispersión de relajación

Evgenia N Nikolova1, Federico L Gottardo, Hashim M Al-Hashimi

  • 1Department of Chemistry and Biophysics, University of Michigan, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|February 8, 2012
PubMed
Resumen

Los pares de bases transitorios de Hoogsteen en el ADN se detectaron directamente utilizando nuevos métodos de RMN. Estos hallazgos revelan enlaces de hidrógeno N-H···N transitorios en el ADN dúplex canónico, avanzando el análisis de la estructura del ácido nucleico.

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