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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

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Los complejos RYBP-PRC1 median la ubicuidad de H2A en los sitios objetivo del policombo independientemente de PRC2 y

Lígia Tavares1, Emilia Dimitrova, David Oxley

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Cell
|February 14, 2012
PubMed
Resumen

El complejo represor de policombos 1 (PRC1) puede ser reclutado independientemente de las marcas H3K27me3. Un nuevo complejo RYBP-PRC1 media esta vía alternativa, impactando el silenciamiento de genes y el silenciamiento mediado por ARN Xist.

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