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Cáncer de mama en el embarazo
Frédéric Amant1, Sibylle Loibl, Patrick Neven
1Multidisciplinary Breast Cancer Center, Leuven Cancer Institute, Katholieke Universiteit Leuven, Belgium. frederic.amant@uzleuven.be
Lancet (London, England)
|February 14, 2012
Resumen
El cáncer de mama en el embarazo se puede manejar de manera segura con atención multidisciplinaria, que incluye cirugía y quimioterapia después de 14 semanas de gestación. Se necesita una cuidadosa consideración de la radioterapia debido a los riesgos fetales.
Área de la Ciencia:
- Oncología Oncología.
- La medicina materno-fetal es una de ellas.
Sus antecedentes:
- El diagnóstico de cáncer de mama durante el embarazo presenta desafíos únicos para el tratamiento y el manejo.
- La atención óptima requiere un enfoque multidisciplinario que considere tanto el bienestar materno como el fetal.
Objetivo del estudio:
- Describir las estrategias actuales basadas en la evidencia para la estadificación y el tratamiento del cáncer de mama durante el embarazo.
- Para resaltar la seguridad y eficacia de varias modalidades de tratamiento en pacientes embarazadas.
Principales métodos:
- Revisión de la literatura existente sobre el manejo del cáncer de mama en mujeres embarazadas.
- Análisis de los resultados del tratamiento basado en la biología del tumor, la etapa y la edad gestacional.
Principales resultados:
- La cirugía es factible en todos los trimestres.
- La radioterapia requiere una cuidadosa evaluación individual debido a los posibles riesgos fetales.
- La quimioterapia se apoya cada vez más a partir de las 14 semanas de gestación en adelante.
- El tamoxifeno y el trastuzumab están contraindicados durante el embarazo.
Conclusiones:
- El manejo multidisciplinario permite un tratamiento seguro y eficaz del cáncer de mama durante el embarazo.
- El tratamiento oportuno puede reducir la incidencia de prematuridad asociada con el embarazo y el cáncer de mama.
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