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Updated: May 24, 2026

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer
08:29

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

Published on: November 1, 2019

El reconocimiento del PCNA modificado por SUMO requiere motivos de receptores en tándem en Srs2

Anthony A Armstrong1, Firaz Mohideen, Christopher D Lima

  • 1Structural Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.

Nature
|March 3, 2012
PubMed
Resumen

La ubiquitina (Ub) y SUMO (Smt3) modifican las proteínas para la señalización celular. Los investigadores descubrieron que la helicasa Srs2 utiliza dos motivos para reconocer específicamente el PCNA modificado por SUMO, crucial para las vías de reparación del ADN.

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