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Estructura del receptor κ-opioide humano en complejo con JDTic

Huixian Wu1, Daniel Wacker, Mauro Mileni

  • 1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Nature
|March 23, 2012
PubMed
Resumen

Los investigadores determinaron la estructura cristalina del receptor humano kappa-opioide (κ-OR) unido a un antagonista. Esto proporciona información clave sobre la selectividad κ-OR y el diseño de fármacos para la regulación del dolor y el estado de ánimo.

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