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Lípidos séricos y lipoproteínas en hombres y mujeres chinos
Wenying Yang1, Jianzhong Xiao, Zhaojun Yang
1Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China. ywy_1010@yahoo.com.cn
Circulation
|April 12, 2012
Resumen
Los niveles altos de colesterol sérico son frecuentes en China.
Área de la Ciencia:
- Epidemiología de las enfermedades cardiovasculares.
- Investigación del metabolismo de los lípidos.
- La salud pública en China.
Sus antecedentes:
- Las enfermedades cardiovasculares son la principal causa de muerte en China, vinculadas a los cambios en el estilo de vida.
- La estimación de los niveles nacionales de lípidos séricos y lipoproteínas es crucial para la salud pública.
- La comprensión de los perfiles lipídicos informa las estrategias de prevención de enfermedades cardiovasculares.
Objetivo del estudio:
- Determinar la prevalencia nacional de lípidos séricos y lipoproteínas en la población adulta china.
- Proporcionar datos actualizados sobre los niveles de colesterol y triglicéridos en toda China.
- Evaluar el estado actual de la conciencia, el tratamiento y el control del colesterol alto.
Principales métodos:
- Se realizó un estudio transversal en una muestra representativa a nivel nacional de 46.239 adultos chinos (de edades ≥20 años).
- Se midió el colesterol sérico total en ayunas, el colesterol de lipoproteínas de alta densidad, el colesterol de lipoproteínas de baja densidad y los triglicéridos.
- Se calcularon estimaciones estandarizadas por edad y porcentajes de población.
Principales resultados:
- El colesterol total sérico promedio fue de 4,72 mmol/L, con un 9,0% de colesterol total alto (≥6,22 mmol/L).
- La media del colesterol lipoproteico de baja densidad fue de 2,68 mmol/L; el 3,0% tenía niveles muy altos (≥4,92 mmol/L).
- El 22,3% tenía bajo colesterol de lipoproteínas de alta densidad (<1,04 mmol/L), y el conocimiento/tratamiento/control del colesterol alto era bajo (11,0%/5,1%/2,8%).
Conclusiones:
- Los niveles de colesterol sérico total y de lipoproteínas de baja densidad son altos y están aumentando en China.
- Las bajas tasas de concienciación, tratamiento y control de la dislipidemia representan un desafío significativo para la salud pública.
- Sin intervenciones efectivas, se prevé que las enfermedades cardiovasculares ateroscleróticas aumenten sustancialmente.
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