Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Transmission-Line Differential Equations01:26

Transmission-Line Differential Equations

Transmission lines are essential components of electrical power systems. They are characterized by the distributed nature of resistance (R), inductance (L), and capacitance (C) per unit length. To analyze these lines, differential equations are employed to model the variations in voltage and current along the line.
Line Section Model
A circuit representing a line section of length Δx helps in understanding the transmission line parameters. The voltage V(x) and current i(x) are measured from the...
Diffusion01:12

Diffusion

Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
Diffusion01:21

Diffusion

Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
Nodal Analysis01:10

Nodal Analysis

Nodal analysis is a fundamental method in electrical engineering used to simplify the process of circuit analysis. This method revolves around the concept of using node voltages as the primary variables for circuit analysis. The objective is to determine the voltage at each node in a circuit, which can then be used to find other quantities of interest, such as currents through specific components.
Consider, for instance, a simple circuit composed of three nodes and three resistors, as shown in...
Boundary Conditions for Current Density01:25

Boundary Conditions for Current Density

Current density becomes discontinuous across an interface of materials with different electrical conductivities. The normal component of the current density is continuous across the boundary.
Nodal Analysis with Voltage Sources01:11

Nodal Analysis with Voltage Sources

Nodal analysis is a remarkably effective method used in electrical engineering to simplify the analysis of complex circuits, including those with dependent or independent voltage sources. Its strength lies in its systematic approach to breaking down circuits into manageable components, making it easier for engineers to understand and solve.
Consider a circuit that contains four resistors and two voltage sources, as shown in Figure 1. One of these voltage sources is connected between a...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Disinhibition of cerebellar output by loss of restless legs syndrome-associated gene MEIS1.

Current biology : CB·2026
Same author

A transgenic zebrafish for direct optogenetic activation of FGF/ERK signaling.

bioRxiv : the preprint server for biology·2026
Same author

An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafish.

Developmental biology·2026
Same author

High-Fidelity Long-term Whole-embryo Lineage and Fate Reconstruction by Iterative Tracking with Error Correction.

bioRxiv : the preprint server for biology·2026
Same author

Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis.

Science (New York, N.Y.)·2026
Same author

Author Correction: Transsynaptic labeling and transcriptional control of zebrafish neural circuits.

Nature neuroscience·2025

Video Experimental Relacionado

Updated: May 23, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

La difusividad diferencial de Nodal y Lefty subyace en un sistema de patrones de reacción-difusión.

Patrick Müller1, Katherine W Rogers, Ben M Jordan

  • 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA. pmueller@fas.harvard.edu

Science (New York, N.Y.)
|April 14, 2012
PubMed
Resumen

La difusividad diferencial, no el aclaramiento, explica las diferencias de rango de señalización en la formación de patrones biológicos. Este estudio apoya los modelos de difusión de reacción para los sistemas activador / inhibidor como Nodal / Lefty en el pez cebra.

Más Videos Relacionados

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells
05:56

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells

Published on: November 12, 2020

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup
09:56

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup

Published on: October 7, 2025

Videos de Experimentos Relacionados

Last Updated: May 23, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells
05:56

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells

Published on: November 12, 2020

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup
09:56

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup

Published on: October 7, 2025

Área de la Ciencia:

  • Biología del desarrollo Biología del desarrollo.
  • La biofísica es la biofísica.
  • Biología de sistemas Biología de sistemas.

Sus antecedentes:

  • La formación de patrones biológicos a menudo implica activadores de corto alcance e inhibidores de largo alcance.
  • Los modelos de reacción-difusión explican las diferencias de rango a través de la difusividad diferencial o el aclaramiento.
  • El sistema Nodal/Lefty en el pez cebra sirve como modelo para estudiar estos mecanismos.

Objetivo del estudio:

  • Para probar experimentalmente si la difusividad diferencial o el aclaramiento diferencial determina los distintos rangos de señalización de Nodal y Lefty.
  • Proporcionar evidencia biofísica que apoye o refuta los modelos existentes de formación de patrones.

Principales métodos:

  • Análisis de gradientes nodal y izquierdo de proteínas en embriones de pez cebra.
  • Experimentos de etiquetado de pulsos para evaluar la cinética del aclaramiento.
  • La recuperación de la fluorescencia después del fotoblanqueamiento (FRAP) se analiza para medir los coeficientes de difusión efectivos.

Principales resultados:

  • Las proteínas nódales exhibieron un rango de señalización más corto en comparación con las proteínas izquierdas.
  • Las proteínas nodal y Lefty demostraron tasas de aclaramiento similares.
  • Las proteínas izquierdistas mostraron un coeficiente de difusión efectivo más alto que las proteínas nódales.

Conclusiones:

  • La difusividad diferencial es el principal factor responsable de los diferentes rangos de señalización de Nodal y Lefty.
  • Estos hallazgos proporcionan un fuerte apoyo biofísico a los modelos de reacción-difusión para explicar el patrón biológico mediado por activador-inhibidor.