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A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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Resolución cinética dinámica de los ésteres α-ceto a través de la hidrogenación por transferencia asimétrica

Kimberly M Steward1, Emily C Gentry, Jeffrey S Johnson

  • 1Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 2799-3290, USA.

Journal of the American Chemical Society
|April 19, 2012
PubMed
Resumen

Un nuevo catalizador de rutenio permite la resolución cinética dinámica de los ceto ésteres, creando moléculas complejas con tres estereocentros. Este eficiente proceso produce valiosas gamma-butirolactonas enriquecidas con enantio para su posterior síntesis.

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