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Biosíntesis de tiamina pirimidina en Candida albicans: una notable reacción entre la histidina y el fosfato de

Rung-Yi Lai1, Siyu Huang, Michael K Fenwick

  • 1Department of Chemistry, Texas A&M University, College Station, 77843, United States.

Journal of the American Chemical Society
|May 10, 2012
PubMed
Resumen

Este estudio identifica la histidina como la fuente para la formación de pirimidina en Candida albicans, utilizando fosfato piridoxal (PLP) y una nueva vía enzimática. La pirimidina sintasa funciona como una enzima de un solo giro, revelando procesos bioquímicos únicos.

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