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Enfoque basado en compuestos de inclusión para matrices de rotores moleculares dipolares artificiales. Una inclusión
Lukáš Kobr1, Ke Zhao, Yongqiang Shen
1Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309, USA.
Journal of the American Chemical Society
|June 2, 2012
Resumen
Los investigadores crearon conjuntos ordenados de rotores moleculares utilizando un sistema anfitrión-invitado. Este método permite controlar la colocación de los rotores, influyendo en su dinámica de rotación y las barreras energéticas para aplicaciones potenciales en maquinaria molecular.
Área de la Ciencia:
- Ciencia de los materiales Ciencia de los materiales.
- Química supramolecular de las moléculas.
- Nanotecnología La nanotecnología es la nanotecnología.
Sus antecedentes:
- Los conjuntos ordenados de rotores moleculares son cruciales para el desarrollo de máquinas moleculares y materiales avanzados.
- Controlar la colocación precisa y la dinámica de los rotores moleculares dentro de una estructura huésped presenta un desafío significativo.
- El Tris ((o-fenilenodioxy) ciclotrifosfazeno (TPP) ofrece un marco de acogida con potencial para acomodar moléculas invitadas en arreglos definidos.
Objetivo del estudio:
- Desarrollar un método para crear matrices triangulares regulares de rotores moleculares dipolares.
- Investigar la influencia de las interacciones huésped-huésped en la dinámica de rotación de los rotores moleculares.
- Para caracterizar la formación y las propiedades de los compuestos de inclusión superficial que involucran rotores moleculares.
Principales métodos:
- Síntesis de un rotor dipolar específico: 1-n-hexadecyl-12-(2,3-diclorofenil) -p-dicarba-closo-dodecaborano. también conocido como 1-n-hexadecyl-12-
- Complejación anfitrión-invitado usando tris ((o-fenilenodioxy) ciclotrifosfazeno (TPP) como el anfitrión.
- Técnicas de caracterización que incluyen calorimetría de barrido diferencial (DSC), espectroscopia de resonancia magnética nuclear (RMN) de estado sólido y difracción de rayos X en polvo (PXRD).
- Espectroscopia dieléctrica para determinar las barreras de rotación.
Principales resultados:
- La inserción exitosa de rotores dipolares en los canales de TPP, formando un compuesto de inclusión de superficie.
- Control demostrado sobre la ubicación del rotor (en masa frente a la superficie) mediante la modificación del eje del rotor con tapones.
- Identificaron barreras de rotación que van desde 1,2 a 9 kcal/mol, dependiendo del grado de inserción del rotor y la interacción de la superficie.
- Evidencia de rotores que interactúan con la superficie anfitriona, influyendo en su libertad de rotación.
Conclusiones:
- El enfoque anfitrión-invitado utilizando TPP permite la formación de matrices ordenadas de rotores moleculares.
- Se pueden formar compuestos de inclusión de superficie, que ofrecen un medio para controlar la dinámica del rotor.
- Las barreras de rotación son sensibles a la profundidad de inserción específica y las interacciones superficiales de los rotores.
- Esta estrategia proporciona un camino para diseñar materiales moleculares funcionales con propiedades sintonizables.
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