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Updated: May 5, 2026

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
09:39

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

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La adenililciclasa AC1 estimulada por Ca(2+) genera un ritmo biológico eficiente como terapia génica única y en

Gerard J J Boink1, Bruce D Nearing, Iryna N Shlapakova

  • 1Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, NY 10032, USA.

Circulation
|July 4, 2012
PubMed
Resumen

La terapia génica que utiliza AC1 o HCN2 / AC1 en el corazón ofrece un ritmo biológico superior y una respuesta autónoma en comparación con HCN2 solo. Este avance mejora el control de la frecuencia cardíaca y la capacidad de adaptación.

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