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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Published on: February 7, 2019

Cambiando la estereoselectividad: (fullero) pirrolidinas "a la carta"

Enrique E Maroto1, Salvatore Filippone, Angel Martín-Domenech

  • 1Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense , E-28040 Madrid, Spain.

Journal of the American Chemical Society
|July 28, 2012
PubMed
Resumen

Este estudio presenta síntesis estereodivergentes para los pirrolidinofullerenos y las pirrolidinas con alta enantioselectividad. Los fullerenos sirven como un punto de referencia para el desarrollo de catalizadores para controlar los resultados estereoquímicos en cicloadiciones 1,3-dipolares.

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