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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Autoensamblaje controlado de múltiples ésteres borónicos macrocíclicos diastereoméricos compuestos por dos unidades

Suguru Ito1, Kosuke Ono, Nobuharu Iwasawa

  • 1Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8551, Japan.

Journal of the American Chemical Society
|August 14, 2012
PubMed
Resumen

Los investigadores desarrollaron un método para sintetizar ésteres borónicos macrocíclicos utilizando el autoensamblaje. Esta técnica creó con éxito cuatro de los cinco diastereómeros, con tres obtenibles en formas enantiopuras.

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