Investigación mecanicista de la metilfosfonato sintasa, una oxigenasa no dependiente del hierro no hemo y dependiente

Heather A Cooke1, Spencer C Peck, Bradley S Evans

  • 1Howard Hughes Medical Institute and Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

PubMed
Resumen

La metilfosfonato sintasa, una enzima dependiente del hierro, convierte el 2-hidroxietilfosfonato (2-HEP) en metilfosfonato. El estudio revela la transferencia estereospecífica de hidrógeno durante esta crucial reacción enzimática.

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