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Updated: May 18, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Síntesis total de (±) -communesin F a través de una cicloadición con indol-2-ona

Johannes Belmar1, Raymond L Funk

  • 1Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

Journal of the American Chemical Society
|September 18, 2012
PubMed
Resumen

Los investigadores lograron una síntesis total concisa de (±) -communesin F en 15 pasos. Una reacción clave de cicloadición construyó rápidamente el núcleo tetraciclico del producto natural, mostrando una estrategia sintética eficiente.

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