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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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Rescate de glicina de las hojas β de la cis-prolina

Madhurima Das1, Gautam Basu

  • 1Bioinformatics Centre, Bose Institute, P-1/12 CIT Scheme VIIM, Kolkata 700054, India.

Journal of the American Chemical Society
|September 20, 2012
PubMed
Resumen

La glicina rescata las distorsiones de la estructura de la hoja beta causadas por la cis-prolina. Este residuo de glicina (Gly(β(PR))) adopta una conformación de poliprolina, preservando la estructura y la función de las proteínas.

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