Video Experimental Relacionado
Updated: Aug 19, 2026
11:38
High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
Problemas identificados por la revisión secundaria de los manuscritos aceptados
J M Garfunkel1, M H Ulshen, H J Hamrick
1Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill 27599-7230.
JAMA
|March 9, 1990
Resumen
La revisión por pares de los manuscritos aceptados reveló defectos, sin embargo, la mayoría aún se recomendó para su publicación. Este estudio cuestiona la fiabilidad de los procesos de revisión de manuscritos en la publicación científica.
Área de la Ciencia:
- La bibliometría y la bibliometría.
- La comunicación académica es la comunicación académica.
- La revisión por pares es una revisión por pares.
Sus antecedentes:
- La aceptación del manuscrito se basa en una rigurosa revisión por pares.
- La fiabilidad de este proceso es crucial para la integridad científica.
Objetivo del estudio:
- Evaluar la coherencia y validez del proceso de revisión por pares.
- Para determinar si los manuscritos aceptados contienen defectos no detectados significativos.
Principales métodos:
- Los manuscritos aceptados fueron revisados nuevamente por nuevos árbitros que no estaban al tanto.
- Los editores asistentes evaluaron la importancia de las críticas de los revisores.
Principales resultados:
- La mayoría de los manuscritos recibieron críticas que justificaban una mayor revisión.
- Los revisores identificaron defectos diferentes en todos los manuscritos.
- A pesar de las fallas identificadas, el 80% se recomendó para su publicación.
Conclusiones:
- El proceso de revisión por pares puede no identificar consistentemente todos los defectos críticos del manuscrito.
- Los manuscritos aceptados a menudo conservan defectos, aunque típicamente no conducen al rechazo.
- Se sugiere un mayor refinamiento de los estándares de revisión por pares.
Videos de Conceptos Relacionados
01:55Secondary Active Transport
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
00:46Feedback Inhibition
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
01:57Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
01:43Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
01:36Mismatch Repair
Overview
01:01Feedback Loops
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.