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BDNF es un modulador negativo de la acción de la morfina

Ja Wook Koo1, Michelle S Mazei-Robison, Dipesh Chaudhury

  • 1Fishberg Department of Neuroscience and Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.

Science (New York, N.Y.)
|October 9, 2012
PubMed
Resumen

El factor neurotrófico derivado del cerebro (BDNF) contrarresta sorprendentemente la recompensa de la morfina mediante la regulación de las neuronas dopaminérgicas en el VTA y el NAc. La supresión del BDNF en el VTA mejora la morfina.

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