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Pequeños ARN de signo opuesto... pero con el mismo valor absoluto
1Department of Molecular Biosciences, Northwestern University, 2205 Tech Drive, Evanston, IL 60208-3500, USA. erik@northwestern.edu
Cell
|December 11, 2012
Resumen
Los ARN Piwi-interactivos (piRNAs) en Oxytricha trifallax distinguen las secuencias genómicas del yo del no yo. Estos piRNA aseguran la retención de las secuencias esenciales, evitando su eliminación del genoma somático.
Área de la Ciencia:
- Biología Molecular Biología Molecular
- Genética La genética.
- ARN Biología Biología ARN
Sus antecedentes:
- Los ARN pequeños en los ciliados median la defensa del genoma eliminando el ADN extraño.
- Los mecanismos de la discriminación genómica del yo versus el no-yo son cruciales para la estabilidad del genoma.
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