La estructura dinámica de los multiméricos de la α-sinucleína

Thomas Gurry1, Orly Ullman, Charles K Fisher

  • 1Computational and Systems Biology Initiative, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA.

Resumen

La alfa-sinucleína, implicada en la enfermedad de Parkinson, existe como monómeros desordenados o multiméricos estructurados. Este estudio revela un conjunto dinámico que incluye oligómeros de hebra helicoidal y beta, conciliando observaciones anteriores.

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