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Un ratón que sigue los pasos de la prehistoria humana
Samuel H Vohr1, Richard E Green
1Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Cell
|February 19, 2013
Resumen
La variante V370A del receptor de Ectodysplasin A (EDAR) muestra una fuerte selección humana. Este estudio revela su origen y utiliza ratones para detallar los efectos fenotípicos de la variante.
Área de la Ciencia:
- Genética evolutiva humana La genética evolutiva humana es la genética evolutiva humana.
- Biología molecular La biología molecular.
- Biología del desarrollo Biología del desarrollo.
Sus antecedentes:
- La variante V370A en el gen del receptor de Ectodysplasin A (EDAR) es un marcador significativo de selección positiva en poblaciones humanas.
- El calendario evolutivo preciso y los resultados fenotípicos específicos impulsados por esta variante siguen siendo incompletamente entendidos.
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