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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Una nueva estrategia para la síntesis eficiente de lactonas de anillo mediano y grande sin alta dilución o adición

Wanxiang Zhao1, Zigang Li, Jianwei Sun

  • 1Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.

Journal of the American Chemical Society
|March 12, 2013
PubMed
Resumen

Presentamos un nuevo método eficiente para sintetizar lactonas medianas y grandes utilizando una nueva estrategia de expansión de anillos. Este enfoque evita la necesidad de una alta dilución o adición lenta, simplificando la producción de lactona.

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