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La enfermedad por reflujo gastroesofágico
Albert J Bredenoord1, John E Pandolfino, André J P M Smout
1Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, Netherlands.
Lancet (London, England)
|March 13, 2013
Resumen
La comprensión de la enfermedad de reflujo gastroesofágico ha evolucionado de la hernia de hiato a la esofagitis y el monitoreo del pH. Los enfoques de tratamiento para este trastorno gastrointestinal común también han cambiado significativamente con el tiempo.
Área de la Ciencia:
- Gastroenterología y Gastroenterología.
- Enfermedades del tracto digestivo.
Sus antecedentes:
- La enfermedad de reflujo gastroesofágico (ERGE) es un trastorno gastrointestinal prevalente.
- Los enfoques diagnósticos históricos incluían la radiología, que inicialmente equiparaba la GORD con la hernia de hiato.
Objetivo del estudio:
- Para rastrear la evolución de la comprensión y el diagnóstico de GORD.
- Examinar los paradigmas cambiantes de tratamiento para la GORD a lo largo de décadas.
Principales métodos:
- Revisión de las modalidades de diagnóstico históricas para GORD.
- Análisis del impacto de los avances tecnológicos en la definición y el tratamiento de GORD.
Principales resultados:
- La definición de GORD pasó de la hernia de hiato (radiología) a la esofagitis (endoscopia).
- El monitoreo del pH esofágico refinó aún más los criterios de diagnóstico.
- Los avances farmacológicos (H2RAs, PPIs) influyeron en las estrategias de tratamiento, lo que llevó a enfoques variados.
Conclusiones:
- La conceptualización y la gestión de GORD han sufrido transformaciones sustanciales.
- Los avances diagnósticos y terapéuticos continúan dando forma al enfoque clínico de la GORD.
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