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Updated: May 13, 2026

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El Zn estructural (II) implica un cambio de plegamiento totalmente cooperativo a plegamiento parcialmente cuesta

Maddalena Palmieri1, Gaetano Malgieri, Luigi Russo

  • 1Department of Environmental, Biological and Pharmaceutical Science and Technology, Second University of Naples , Via Vivaldi 43, 81100 Caserta, Italy.

Journal of the American Chemical Society
|March 15, 2013
PubMed
Resumen

El ion zinc en la proteína Ros87 cambia su despliegue de un solo paso a un proceso de dos pasos. Este hallazgo ofrece nuevos conocimientos sobre los roles de los iones metálicos en el mal plegamiento de las proteínas y las enfermedades neurodegenerativas.

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