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Updated: May 6, 2026

Isolation and Derivation of Mouse Embryonic Germinal Cells
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Published on: October 22, 2009

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PRC1 coordina el tiempo de diferenciación sexual de las células germinales primordiales femeninas

Shihori Yokobayashi1, Ching-Yeu Liang, Hubertus Kohler

  • 1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.

Nature
|March 15, 2013
PubMed
Resumen

La dosificación del gen del complejo represor de policombos 1 (PRC1) es crucial para el desarrollo de células germinales de mamíferos. PRC1 antagoniza la señalización del ácido retinoico, asegurando la diferenciación sexual oportuna de las células germinales femeninas y evitando la meiosis precoz.

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