Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Redox Titration: Other Oxidizing and Reducing Agents01:26

Redox Titration: Other Oxidizing and Reducing Agents

Besides iodine, other oxidizing or reducing agents can serve as titrants in redox titrations. Common oxidizing titrants include KMnO4, cerium(IV), and K2Cr2O7. The choice of oxidizing titrants depends on factors like stability, cost, analyte strength, and reaction rate between the analyte and titrant. KMnO4 is a strong oxidizing titrant that reduces from Mn(VII) to Mn(II) in a highly acidic solution, simultaneously oxidizing the analyte to a higher oxidation state. In this case, KMnO4 acts as a...
Redox Reactions01:24

Redox Reactions

Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Colors and Magnetism03:02

Colors and Magnetism

Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human eye.
Radical Oxidation of Allylic and Benzylic Alcohols01:21

Radical Oxidation of Allylic and Benzylic Alcohols

Activated manganese(IV) oxide can selectively oxidize allylic and benzylic alcohols via a radical intermediate mechanism. Primary allylic alcohols are oxidized to aldehydes, while secondary allylic alcohols yield ketones. The redox reaction of potassium permanganate with an Mn(II) salt such as manganese sulfate (under either alkaline or acidic conditions), followed by thorough drying, yields the oxidizing agent: activated MnO2. While MnO2 is insoluble in the solvents used for the reaction, the...
Redox Titration: Overview01:21

Redox Titration: Overview

Redox titration is a chemical analysis technique used to determine the concentration of an unknown substance by measuring the electron transfer in a redox (reduction-oxidation) reaction. The process involves gradually adding a titrant with a known concentration of an oxidizing or reducing agent, to the analyte, the solution with an unknown concentration, until reaching the endpoint, which indicates the completion of the reaction between the two substances. Ensuring the analyte is in a single...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Dynamic contrast-enhanced MRI quantifies microvascular changes in lung transplant recipients with chronic lung allograft dysfunction.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Collagen-binding ⁶⁸Ga-CBP8 PET/MR in Deep Pelvic Endometriosis: First-in-human Application.

Molecular imaging and biology·2026
Same author

Estimation of Absolute Protein-DNA Binding Free Energy Using Streamlined Geometric Formalism.

The journal of physical chemistry letters·2026
Same author

Novel biomarker of fibrosis in SSc-ILD.

RMD open·2026
Same author

Contrast-sparing CT using renal-clearable gold nanoclusters for early spatial mapping of renal dysfunction.

Science advances·2026
Same author

Chris Orvig: Celebrating His Career and Contributions to Inorganic Biochemistry.

Journal of inorganic biochemistry·2026

Video Experimental Relacionado

Updated: May 13, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
09:02

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate

Published on: June 18, 2020

Agente de contraste MR basado en manganeso activado por redox basado en manganeso.

Galen S Loving1, Shreya Mukherjee, Peter Caravan

  • 1A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 2301, Charlestown, Massachusetts 02129, USA.

Journal of the American Chemical Society
|March 21, 2013
PubMed
Resumen

Este estudio introduce un complejo de coordinación de manganeso (Mn) como una nueva sonda de imágenes de resonancia magnética (MR) sensible al redox. Demuestra un cambio significativo de la señal MR en respuesta al glutatión y al peróxido de hidrógeno.

Más Videos Relacionados

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

Videos de Experimentos Relacionados

Last Updated: May 13, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
09:02

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate

Published on: June 18, 2020

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

Área de la Ciencia:

  • Imágenes biomédicas de imágenes.
  • Química Inorgánica La química inorgánica es la química inorgánica.
  • Ciencia de los materiales Ciencia de los materiales.

Sus antecedentes:

  • Las imágenes por resonancia magnética (RM) son una herramienta de diagnóstico crucial.
  • El desarrollo de agentes de contraste sensibles y sensibles es esencial para las imágenes avanzadas de resonancia magnética.
  • Los complejos de manganeso (Mn) ofrecen potencial como agentes de contraste MR debido a sus propiedades paramagnéticas.

Objetivo del estudio:

  • Desarrollar una nueva sonda de imagen de resonancia magnética (RM) basada en manganeso sensible al redox.
  • Investigar la utilidad de un complejo específico de coordinación de Mn con un ligando HBET para detectar cambios redox biológicos.
  • Para caracterizar los cambios de relaxividad del complejo Mn bajo diferentes condiciones de redox.

Principales métodos:

  • Síntesis y caracterización de un complejo de coordinación manganeso-HBET.
  • Evaluación de la estabilidad del complejo en los estados de oxidación Mn(2+) y Mn(3+).
  • Evaluación de los cambios de relaxividad en la presencia de glutatión (GSH) y peróxido de hidrógeno (H2O2).
  • Mediciones de la señal MR para cuantificar los cambios inducidos por los agentes redox.

Principales resultados:

  • El ligando HBET estabiliza efectivamente tanto los estados de oxidación Mn(2+) como Mn(3+).
  • En presencia de glutatión (GSH), el Mn(III) -HBET se convierte en Mn(II) -HBET, lo que resulta en un aumento de tres veces en la relaxividad y la señal de MR.
  • El peróxido de hidrógeno (H2O2) convierte el Mn(II) -HBET de nuevo en Mn(III) -HBET, lo que lleva a una disminución de la señal de MR.

Conclusiones:

  • El complejo Mn-HBET desarrollado funciona como una sonda MR sensible a la reacción redox sensible.
  • La sonda exhibe distintos cambios en la señal MR en respuesta a especies redox biológicamente relevantes como GSH y H2O2.
  • Este complejo de coordinación de Mn es prometedor para aplicaciones avanzadas de imágenes de resonancia magnética con sensibilidad redox.