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Updated: May 12, 2026

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts
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Disrupción reversible de los complejos mSWI/SNF (BAF) por la fusión oncogénica SS18-SSX en el sarcoma sinovial

Cigall Kadoch1, Gerald R Crabtree

  • 1Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Cell
|April 2, 2013
PubMed
Resumen

Las mutaciones en los complejos SWI / SNF (BAF) son comunes en los cánceres humanos. En el sarcoma sinovial, la proteína de fusión SS18-SSX interrumpe los complejos BAF, activando el gen Sox2 y impulsando el crecimiento tumoral.

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