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El ensamblaje de la red de actina nuclear por las forminas regula el coactivador del SRF MAL

Christian Baarlink1, Haicui Wang, Robert Grosse

  • 1Institute of Pharmacology, Biochemical-Pharmacological Center, University of Marburg, Germany.

Science (New York, N.Y.)
|April 6, 2013
PubMed
Resumen

Las forminas construyen filamentos de actina en el núcleo, activando la actividad transcripcional del factor de respuesta sérica (SRF). Este conjunto de actina nuclear, impulsado por forminas como mDia, es clave para la respuesta sérica de la célula.

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